Plasticity in medaka gonadotropes via cell proliferation and phenotypic conversion

New article on gonadotrope cell plasticity In medaka

Together with Erill Ager-Wick, Kjetil Hodne and Finn-Arne Weltzien, we have published a new article entitled Plasticity in medaka gonadotropes via cell proliferation and phenotypic conversion in Journal of Endocrinology.

Using a combination of in vivo and in vitro experiments, our results reveal high plasticity of gonadotropes due to both estradiol-sensitive proliferation and Gnrh-promoted phenotypic conversion, and moreover show that gonadotropes lose part of their identity when kept in cell culture.

This article is in open access, and can be obtained here: https://doi.org/10.1530/JOE-19-0405

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